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Revisions were made to the ISO 14644-1 and -2 regulations in November 2015, coming into effect in January 2016. Because these standards regulate the classification of airborne cleanliness, the changes impact companies in a wide range of industries – anywhere that a clean-room is utilized. In this document, we provide a comprehensive overview of the new ISO 14644-1 regulations.
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Removing a HEPA filter and installing a new one is a process that needs to be handled carefully to ensure the safety of workplace personnel and prevent damage to the filter. If mismanaged, it could result in exposure to high concentrations of harmful organisms. If the HEPA filter is part of a bio-safety cabinet, a full decontamination must be done using gases to neutralise the threats.
It is also possible to use a bag-in, bag-out system in some cases. This is where the old filter is removed in a sealed bag, and a new one inserted in a sealed bag. However, this needs to be set up when the filter-containing equipment is initially installed and all servicing must be carried out by trained personnel.
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